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TIM-3 increases the abundance of type-2 dendritic cells during Leishmania donovani infection by enhancing IL-10 production via STAT3.
Mishra M, Yadav M, Kumar S, Kumar R, Sen P. Mishra M, et al. Cell Death Dis. 2023 May 18;14(5):331. doi: 10.1038/s41419-023-05848-3. Cell Death Dis. 2023. PMID: 37202419 Free PMC article.
We also found that LD actually upregulated TIM-3 expression on DCs by triggering a TIM-3-mediated signaling pathway STAT3 (signal transducer and activator of transcription 3)interleukin (IL)-10c-Srctranscription factors Ets1, Ets2, USF1, and USF2. Notably, TIM-3 pro …
We also found that LD actually upregulated TIM-3 expression on DCs by triggering a TIM-3-mediated signaling pathway STAT3 (signal transducer …
Exogenous nucleosides modulate expression and activity of transcription factors in Caco-2 cells.
Ortega Á, Gil Á, Sánchez-Pozo A. Ortega Á, et al. J Nutr Biochem. 2011 Jun;22(6):595-604. doi: 10.1016/j.jnutbio.2010.05.003. Epub 2010 Oct 20. J Nutr Biochem. 2011. PMID: 20970311
The addition of NSs to the media increased the expression and activity of the TFs CCAAT displacement protein (CUX1), v-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1) and SMAD family member 2. In contrast, NS addition decreased the expression and activity of …
The addition of NSs to the media increased the expression and activity of the TFs CCAAT displacement protein (CUX1), v-ets avian erythroblas …
c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor.
Gujar R, Maurya N, Yadav V, Gupta M, Arora S, Khatri N, Sen P. Gujar R, et al. J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104. Epub 2016 Jul 20. J Immunol. 2016. PMID: 27439518
In this study, we have identified a novel signaling pathway (c-SrcBruton's tyrosine kinasetranscription factors Ets1, Ets2, USF1, and USF2) necessary for TIM-3 upregulation on DCs. ...Suppressed expression of c-Src or downstream Bruton's tyrosine kinase, Ets1 …
In this study, we have identified a novel signaling pathway (c-SrcBruton's tyrosine kinasetranscription factors Ets1, Ets2, USF1 …